When not to use NexGard?

When Not to Use NexGard: A Comprehensive Guide

NexGard is a powerful and popular flea and tick preventative, but it’s not always the right choice for every dog. Knowing when not to use NexGard is crucial to protecting your pet’s health and well-being.


Introduction: The Rise of Oral Flea and Tick Preventatives

Oral flea and tick preventatives like NexGard have revolutionized pet care, offering a convenient and effective alternative to traditional topical treatments. However, with any medication, it’s essential to understand the potential risks and contraindications. This article provides a comprehensive guide on when not to use NexGard, empowering you to make informed decisions about your dog’s health.

What is NexGard and How Does It Work?

NexGard contains the active ingredient afoxolaner, an isoxazoline that interferes with the nervous system of fleas and ticks. Once ingested, afoxolaner is absorbed into the dog’s bloodstream. When fleas and ticks feed on the treated dog, they ingest the afoxolaner, which paralyzes and kills them. NexGard is typically administered monthly and provides protection against fleas and several common tick species.

Benefits of Using NexGard

NexGard offers several benefits, including:

  • Convenience: Easy to administer, just a chewable tablet.
  • Effectiveness: Kills fleas and ticks quickly and effectively.
  • Water Resistance: Not affected by bathing or swimming.
  • Broad Spectrum: Protects against multiple tick species.

Potential Risks and Side Effects

While NexGard is generally safe for most dogs, it’s important to be aware of potential risks and side effects. Some dogs may experience vomiting, diarrhea, lethargy, or decreased appetite. In rare cases, more serious neurological side effects, such as seizures, have been reported. It’s crucial to monitor your dog closely after administering NexGard and to contact your veterinarian immediately if you notice any adverse reactions.

Understanding Isoxazolines and Their Potential Impact

Isoxazolines, the drug class to which afoxolaner belongs, have been associated with neurological adverse events, particularly in dogs with a pre-existing history of seizures or neurological disorders. While the exact mechanism is still under investigation, it’s believed that isoxazolines can lower the seizure threshold in susceptible animals.

Determining When NexGard is Not the Right Choice

When not to use NexGard? Several factors should be considered:

  • History of Seizures: Dogs with a history of seizures or neurological disorders should typically avoid NexGard. Alternative flea and tick preventatives should be considered.
  • Drug Sensitivities: If your dog has had an allergic reaction or sensitivity to isoxazolines or any other ingredient in NexGard, it should not be used.
  • Breeding, Pregnant, or Lactating Dogs: The safety of NexGard in breeding, pregnant, or lactating dogs has not been fully established, and caution is advised. Consult your veterinarian for guidance.
  • Puppies Under 8 Weeks Old: NexGard is not approved for use in puppies younger than 8 weeks old or weighing less than 4 pounds.
  • Certain Medical Conditions: Dogs with certain underlying medical conditions, such as liver or kidney disease, may be more susceptible to adverse effects from NexGard. Consult your veterinarian before using NexGard in these cases.

Alternative Flea and Tick Preventatives

If NexGard is not suitable for your dog, several alternative flea and tick preventatives are available:

  • Topical Treatments: Spot-on treatments like Frontline or Advantage remain effective options.
  • Flea and Tick Collars: Collars like Seresto offer long-lasting protection.
  • Other Oral Medications: Alternatives containing different active ingredients may be considered under veterinary supervision.
Preventative Type Examples Pros Cons
——————- ——————– ————————————————- ——————————————————————–
Topical Frontline, Advantage Easy to apply, widely available Can be messy, may have limited tick protection
Collar Seresto Long-lasting protection, less frequent application May cause skin irritation, potential for accidental removal
Oral (Alternative) Simparica Trio Broad spectrum, convenient administration May still have potential side effects, requires veterinary prescription

The Importance of Veterinary Consultation

Before starting any flea and tick preventative, including NexGard, it’s crucial to consult with your veterinarian. They can assess your dog’s individual health history, lifestyle, and risk factors to determine the most appropriate and safest option.


Frequently Asked Questions (FAQs)

What are the signs of a NexGard overdose in dogs?

Signs of a NexGard overdose can include vomiting, diarrhea, excessive salivation, muscle tremors, seizures, and incoordination. If you suspect your dog has received an overdose of NexGard, contact your veterinarian or an emergency veterinary clinic immediately.

Can NexGard cause seizures in dogs?

While NexGard is generally safe, there have been reports of seizures in dogs, particularly those with a pre-existing history of seizures or neurological disorders. If your dog experiences a seizure after taking NexGard, contact your veterinarian immediately.

Is NexGard safe for puppies?

NexGard is approved for use in puppies 8 weeks of age or older and weighing 4 pounds or greater. It is not recommended for younger or smaller puppies.

Can I give NexGard to my pregnant dog?

The safety of NexGard in pregnant or lactating dogs has not been fully established. Consult your veterinarian before using NexGard in these cases.

What should I do if my dog has a reaction to NexGard?

If your dog experiences an adverse reaction to NexGard, such as vomiting, diarrhea, lethargy, or seizures, contact your veterinarian immediately. They can provide appropriate treatment and guidance.

Are there any drug interactions with NexGard?

While NexGard is generally considered safe to use with other medications, it’s important to inform your veterinarian about all medications your dog is currently taking to avoid potential drug interactions.

How long does NexGard last?

NexGard provides one month of protection against fleas and ticks. It should be administered monthly for year-round protection.

Does NexGard kill ticks instantly?

NexGard kills fleas and ticks within 24 hours of infestation. It may take up to 48 hours to kill certain tick species.

What is the difference between NexGard and NexGard SPECTRA?

NexGard protects against fleas and ticks, while NexGard SPECTRA provides broader protection against fleas, ticks, heartworm disease, and intestinal worms.

What are the alternatives to NexGard for flea and tick prevention?

Alternatives to NexGard include topical treatments, flea and tick collars, and other oral medications containing different active ingredients. Consult your veterinarian to determine the best option for your dog.

How often should I give my dog NexGard?

NexGard should be administered monthly for year-round protection against fleas and ticks.

Why is it important to consider when not to use NexGard?

Understanding when not to use NexGard is crucial because it helps prevent potentially harmful side effects, especially in vulnerable dogs such as those with a seizure history, puppies under 8 weeks, or breeding females. Prioritizing your dog’s safety through informed decision-making is paramount.

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